Ayesha Khan, currently a contestant on Bigg Boss 17, has had a varied career in modeling and acting. Born and raised in India, she follows Islam and is fluent in Hindi, English, and Marathi. Ayesha began her modeling career in her teens, winning the title of Miss Teen Naviwood in 2019. She quickly rose in popularity and participated in various fashion shows and brand photoshoots.

Ayesha gained recognition through her appearances in Punjabi music videos, such as Mohabbat Ke Kabil (2021), Reborn Heer (2022), and Taveez (2022). She then made her acting debut on television with Baalveer Returns in 2020, where she played the role of Birba​.

In 2022, she transitioned to films, starring in the Telugu movie Mukhachitram, where she portrayed Maya Fernandez. She also appeared in the film Guttu Chappudu​. Additionally, Ayesha has worked as an assistant director and had a minor role in the Hindi TV show Kasautii Zindagii Kay (Season 2).